Play-offs 2nd leg
| Date 日期 | Time 時間 | Home 主場 | Away 客場 | Result 結果 |
| 2011-08-25 | 17:00 | Spartak Moskva | Legia | 2:3 |
| 2011-08-25 | 17:15 | Dinamo Bucureşti | Vorskla | 2:3 |
| 2011-08-25 | 18:30 | Rennes | Crvena zvezda | 4:0 |
| 2011-08-25 | 18:45 | PSV | Ried | 5:0 |
| 2011-08-25 | 19:00 | Alania | Beşiktaş | 2:0 |
| 2011-08-25 | 19:00 | AEK Larnaca | Rosenborg | 2:1 |
| 2011-08-25 | 19:00 | Spartak Trnava | Lokomotiv Moskva | 1:1 |
| 2011-08-25 | 19:00 | Dynamo Kyiv | Litex | 1:0 |
| 2011-08-25 | 19:00 | Dinamo Tbilisi | AEK | 1:1 |
| 2011-08-25 | 19:00 | Gaz Metan | Austria Wien | 1:0 |
| 2011-08-25 | 19:30 | H. Tel-Aviv | Ekranas | 4:0 |
| 2011-08-25 | 19:30 | CSKA Sofia | Steaua | 1:1 |
| 2011-08-25 | 19:30 | Schalke | HJK | 6:1 |
| 2011-08-25 | 19:30 | Young Boys | Braga | 2:2 |
| 2011-08-25 | 20:00 | Rapid Bucureşti | Śląsk | 1:1 |
| 2011-08-25 | 20:00 | Sparta Praha | Vaslui | 1:0 |
| 2011-08-25 | 20:15 | Panathinaikos | M. Tel-Aviv | 2:1 |
| 2011-08-25 | 20:15 | Helsingborg | Standard | 1:3 |
| 2011-08-25 | 20:30 | Vitória SC | Atlético | 0:4 |
| 2011-08-25 | 20:30 | Partizan | Shamrock Rovers | 1:2 |
| 2011-08-25 | 20:30 | Anderlecht | Bursaspor | 2:2 |
| 2011-08-25 | 20:30 | Trabzonspor | Athletic | Match cancelled |
| 2011-08-25 | 20:30 | Rangers | Maribor | 1:1 |
| 2011-08-25 | 20:30 | Dnipro | Fulham | 1:0 |
| 2011-08-25 | 20:30 | Sion | Celtic | 3:1 |
| 2011-08-25 | 20:30 | Club Brugge | Zestafoni | 2:0 |
| 2011-08-25 | 20:45 | Sochaux | Metalist | 0:4 |
| 2011-08-25 | 20:45 | Roma | Slovan Bratislava | 1:1 |
| 2011-08-25 | 20:45 | Rabotnicki | Lazio | 1:3 |
| 2011-08-25 | 20:45 | Birmingham | Nacional | 3:0 |
| 2011-08-25 | 20:45 | Stoke | Thun | 4:1 |
| 2011-08-25 | 20:45 | AZ | Aalesund | 6:0 |
| 2011-08-25 | 21:00 | PSG | Differdange | 2:0 |
| 2011-08-25 | 21:00 | Karpaty | PAOK | 1:1 |
| 2011-08-25 | 21:00 | Tottenham | Hearts | 0:0 |
| 2011-08-25 | 21:05 | Salzburg | Omonia | 1:0 |
| 2011-08-25 | 21:05 | Sevilla | Hannover | 1:1 |
| 2011-08-25 | 22:15 | Sporting | Nordsjælland | 2:1 |
